IIT Roorkee, 10, 02 2025: Scientists at the Indian Institute of Technology Roorkee (IIT Roorkee) have uncovered a crucial regulatory mechanism in Acinetobacter baumannii, a highly drug-resistant superbug responsible for life-threatening infections. Their study, published in mBio, the prestigious journal of the American Society for Microbiology (ASM), reveals how the pathogen controls its attack and defense systems, paving the way for new treatment strategies.

Acinetobacter baumannii is notorious for its ability to resist multiple antibiotics, making it a serious threat in healthcare settings. It causes severe hospital-acquired infections, including pneumonia, bloodstream infections, and urinary tract infections. A major survival tool of this superbug is the Type 6 Secretion System (T6SS) – a bacterial “weapon” used to attack competing microbes. However, how A. baumannii regulates T6SS while maintaining antibiotic resistance has remained unclear until now.

The research team, led by Prof. Ranjana Pathania, discovered that A. baumannii switches T6SS on or off based on environmental conditions. A small RNA molecule, AbsR28, plays a key role in this regulation, influenced by manganese (Mn²+) levels. When Mn²+ levels are high, AbsR28 binds to an essential gene (tssM) required for T6SS function, leading to its degradation. This prevents the activation of T6SS and enables A. baumannii to retain plasmid pAB3, which carries multiple antibiotic-resistance genes.

“We found that when A. baumannii activates T6SS, it becomes more vulnerable to antibiotics and oxidative stress. So, the bacteria must carefully regulate this system to survive in different conditions,” said Prof. Pathania. “Our discovery sheds light on how this pathogen adapts during infections, helping it evade both antibiotics and the immune system.”

By targeting AbsR28, scientists may be able to disrupt the superbug’s regulatory system, making it more susceptible to antibiotics without directly attacking resistance genes. This discovery opens new avenues for precision medicine and novel drug development against multidrug-resistant infections.

The research team includes Somok Bhowmik, Avik Pathak, Shivam Pandey, Kuldip Devnath, Abhiroop Sett, Nishant Jyoti, Timsy Bhando, Jawed Akhter, Saurabh Chugh, Dr. Ramandeep Singh, and Tarun Kumar Sharma. Their pioneering work reinforces IIT Roorkee’s leadership in cutting-edge biomedical research.

Prof. Kamal Kishore Pant, Director, IIT Roorkee, said, “At IIT Roorkee, we are committed to advancing scientific research that addresses global health challenges. This breakthrough in understanding Acinetobacter baumannii’s defense mechanism is a testament to the high-impact work being carried out by our researchers. Such discoveries pave the way for innovative solutions in tackling antibiotic resistance and improving healthcare outcomes.”

Mumbai, February 10th, 2025: Ageas Federal Life Insurance, a leading private life insurer in India, has launched its latest investment offering—the Momentum Growth Fund. Opening February 10th – February 21st 2025, this new offering presents an attractive opportunity for investors aiming to benefit from India’s robust long-term economic growth within the ULIP segment. It is strategically aligned with the Nifty 500 Momentum 50 Index, which has delivered remarkable returns of 25.97%* CAGR over the past five years, and 22.90% CAGR since its inception.

With a focus on delivering strong returns over the medium to long term, the fund diversifies investments across a wide range of companies and sectors within the index, helping to mitigate risk while promoting steady, sustainable growth. This disciplined, strategic approach offers customers a rewarding and resilient investment strategy that is well-aligned with India’s thriving economy.

Mr. Jude Gomes, MD & CEO of Ageas Federal Life Insurance, said, “With a GDP of 6.4% in FY 25, India still remains the fastest growing economy. At Ageas Federal Life Insurance, we support the government’s vision for India’s growth story. The Momentum Growth Fund reflects our commitment while empowering customers with solutions that meet their long-term financial aspirations. With this launch, we aim to bridge individual wealth creation and national progress, contributing to India’s extraordinary growth story and fostering a future of shared prosperity.”

The fund empowers investors to navigate the ever-changing stock market trends effectively, while removing any potential fund manager bias. Additionally, it offers the advantage of comprehensive life coverage through Ageas Federal’s innovative and customer-centric insurance plans. The Momentum Growth Fund will be available alongside Ageas Federal Life Insurance’s flagship offerings.

IIT Roorkee, 10, 02 2025: Scientists at the Indian Institute of Technology Roorkee (IIT Roorkee) have uncovered a crucial regulatory mechanism in Acinetobacter baumannii, a highly drug-resistant superbug responsible for life-threatening infections. Their study, published in mBio, the prestigious journal of the American Society for Microbiology (ASM), reveals how the pathogen controls its attack and defense systems, paving the way for new treatment strategies.

Acinetobacter baumannii is notorious for its ability to resist multiple antibiotics, making it a serious threat in healthcare settings. It causes severe hospital-acquired infections, including pneumonia, bloodstream infections, and urinary tract infections. A major survival tool of this superbug is the Type 6 Secretion System (T6SS) – a bacterial “weapon” used to attack competing microbes. However, how A. baumannii regulates T6SS while maintaining antibiotic resistance has remained unclear until now.

The research team, led by Prof. Ranjana Pathania, discovered that A. baumannii switches T6SS on or off based on environmental conditions. A small RNA molecule, AbsR28, plays a key role in this regulation, influenced by manganese (Mn²+) levels. When Mn²+ levels are high, AbsR28 binds to an essential gene (tssM) required for T6SS function, leading to its degradation. This prevents the activation of T6SS and enables A. baumannii to retain plasmid pAB3, which carries multiple antibiotic-resistance genes.

“We found that when A. baumannii activates T6SS, it becomes more vulnerable to antibiotics and oxidative stress. So, the bacteria must carefully regulate this system to survive in different conditions,” said Prof. Pathania. “Our discovery sheds light on how this pathogen adapts during infections, helping it evade both antibiotics and the immune system.”

By targeting AbsR28, scientists may be able to disrupt the superbug’s regulatory system, making it more susceptible to antibiotics without directly attacking resistance genes. This discovery opens new avenues for precision medicine and novel drug development against multidrug-resistant infections.

The research team includes Somok Bhowmik, Avik Pathak, Shivam Pandey, Kuldip Devnath, Abhiroop Sett, Nishant Jyoti, Timsy Bhando, Jawed Akhter, Saurabh Chugh, Dr. Ramandeep Singh, and Tarun Kumar Sharma. Their pioneering work reinforces IIT Roorkee’s leadership in cutting-edge biomedical research.

Prof. Kamal Kishore Pant, Director, of IIT Roorkee, said, “At IIT Roorkee, we are committed to advancing scientific research that addresses global health challenges. This breakthrough in understanding Acinetobacter baumannii’s defense mechanism is a testament to the high-impact work being carried out by our researchers. Such discoveries pave the way for innovative solutions in tackling antibiotic resistance and improving healthcare outcomes.”

Gurugram, 10th Feb 2025: SAMHI Hotels Limited is proud to announce its collaboration with the Indian School of Hospitality, a renowned institution specializing in management and leadership development, to introduce an exclusive Management Development Programme for senior leaders. This initiative aims to foster innovation, strategic thinking, and leadership excellence within the hospitality sector.

The program, launched on 3rd February 2025, is tailored for senior executives at the various hotels under the umbrella of SAMHI Hotels Limited to equip them with cutting-edge skills in leadership, operational finance, and business strategy. Participants will engage in a curriculum designed by the Indian School of Hospitality, known for its expertise in Hospitality Management, Finance, Leadership, and Strategy.

The program has been designed and contextualised to the needs of hospitality leaders of today and would include experiential workshops, case studies, mentorship, and hands-on action learning projects, ensuring participants gain practical insights and tools to address the challenges of a dynamic global market.

“We are very excited to partner with the Indian School of Hospitality to create a bespoke program for emerging leaders across our hotel portfolio,” said Ashish Jakhanwala, Chairman, MD & CEO of SAMHI Hotels. “As we invest capital to grow our hotel portfolio, we also remain committed to investing in developing talent. What makes this unique is that the program is available to leaders across different brands that our hotels operate under and therefore the cohort itself brings phenomenal experience to the classroom”

Indian School of Hospitality is delighted to partner with SAMHI Hotels Limited to deliver this bespoke leadership program,” said Mr Dilip Puri, Founder and Executive Chairman, of Indian School of Hospitality. “Our goal is to empower leaders with the knowledge and skills to drive organizational success and adapt to the evolving demands of the hospitality sector.”

Chennai, Tamil Nadu India- 10 Feb 2025- If you’ve ever wished for a cinema-like experience without the hassle of mounting a projector far from your screen, Zebronics has just dropped the ultimate solution. Introducing the Zeb-Pixa Play Pro 500, an Ultra Short Throw (UST) projector from a homegrown brand. This powerhouse is here to redefine how we experience big-screen entertainment at home.

A true big-screen experience in just a small space—The Zeb – Pixa Play Pro 500 can project a massive 228cm screen size from as close as 40cm away! With an impressive 12500 lumens brightness and Full HD 1080p native resolution, it delivers crystal-clear visuals with rich, vibrant colors. Say goodbye to cluttered setups and mounting hassles—this UST projector transforms even compact spaces into a cinematic experience.

But it’s not just about the visuals. Zebronics packed this projector with multi-connectivity options, including BT v5.0, dual USB, and HDMI&AUX output, so you can hook up everything from your gaming console to your streaming device with ease. Additionally, Miracast and iOS Screen Casting ensure smooth wireless mirroring, eliminating the need for extra cables.

Electronic Focus via Remote – Adjust focus effortlessly from your couch

Air Mouse – Navigate like a pro with intuitive controls

Quad-Core Processor – Ensuring smooth performance, even for heavy tasks like gaming with Android 9 and a 2GB RAM

Dual-band Wi-Fi (2.4GHz & 5GHz) – Lag-free streaming and connectivity

App Support – Access your favorite apps directly

20,000-hour LED lamp life – Built to last for years

Built-in Powerful Speakers – A complete audiovisual experience

The Zeb-Pixa Play Pro 500 projector is designed for movie buffs, gamers, and anyone who wants to bring the big screen home. The Zeb-Pixa Play Pro 500 is now available at Amazon and Flipkart at an introductory price.

Speaking on the launch, Co-Founder & Director – Mr. Pradeep Doshi stated – “At Zebronics, we’ve always believed that world-class technology shouldn’t be a privilege—it should be for everyone& that led us to launch the Zeb-Pixa Play Pro 500 and thereby as India’s first homegrown brand to introduce a UST projector, we are elevating Home Entertainment to new heights. Imagine pairing this with our powerful Zebronics Soundbars—a seamless home theatre experience that brings immersive sound and stunning visuals together effortlessly. And this is just the beginning! We’re committed to bringing more innovations that deliver Premium for Masses, making high-end tech accessible without compromise. With every launch, we’re raising the bar, setting new standards, and staying Always Ahead.”

New Delhi, 10th, February 2025: Career Launcher, a pioneer in UPSC CSAT coaching, has announced the relaunch of its comprehensive CSAT preparation program for the Civil Service Examination 2025. With the rising difficulty of the CSAT paper in recent years, this move addresses the growing demand from students seeking structured guidance to secure qualifying marks. Career Launcher is leveraging its 29+ years of expertise in aptitude training to help aspirants navigate this critical component of the UPSC prelims exam.

Career Launcher first introduced CSAT coaching in 2011, becoming the go-to choice for aspirants with its structured curriculum, experienced faculty, and comprehensive resources. Between 2012 and 2014, its students achieved a remarkable 7% success rate in the prelims examination—more than double the overall success ratio at the time. However, when CSAT became a qualifying paper in 2014, Career Launcher discontinued the program as aspirants required minimal preparation to meet the passing criteria. In recent years, the growing complexity of the CSAT paper has made it challenging for many students to clear this hurdle, sparking demand for expert guidance.

The new CSAT batch will commence on 17th February 2025 and will feature 150+ hours of live interactive online classes, offering in-class practice and doubt-solving sessions. Students enrolling in the program will receive comprehensive hard copy study materials and access to a full-length CSAT test series. The test series will be available in both offline and online modes to accommodate diverse learning preferences and simulate real exam conditions.

Speaking about the relaunch, Gautam Puri, Vice Chairman and MD – UPSC at Career Launcher, said, “We are thrilled to reintroduce our CSAT preparation course to address the increasing challenges faced by UPSC aspirants, especially in prelims. With our unparalleled experience in aptitude coaching and a legacy of success, we aim to provide students with the tools they need to excel and achieve their aspirations. We are committed to making competitive exams easy for students and aspirants using the latest technological tools and our rich experience.”

By, Dr. Smrithi D Nayak, Consultant – Obstetrics &Gynaecology, Aster RV Hospital

Winter in India introduces a specific set of issues and opportunities for those who want to start or expand their families. Here’s how the cold time of the year may play with fertility, along with some tips to make the best of it:

1. Improved Fertility: Hormones in action during Winters
There are changes in hormones that happen normally at this time. Researchers have found that during the winter, levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) are made at a greater rate, thus bringing quality to ovulation and sperm. Most men notice a peak in testosterone during winter and women notice regularity of their cycles, increasing their chances of conceiving.

Pro Tip: Keep a close eye on ovulation during this time and have intercourse during your fertile window for maximum success.

2. Improved Sperm Quality in Men
The cooler temperatures are more favorable to sperm production and quality. Heat can damage sperm, but winter’s cooler climate maintains an ideal environment, thus boosting sperm count and motility.

Pro Tip: Advise your partner to avoid overly tight clothing and hot baths to maintain optimum sperm health throughout winter.

3. Seasonal Diet Boosts Fertility
Winter has plenty of fertility-enhancing foods, such as green leafy vegetables (spinach, fenugreek), fresh citrus fruits (oranges, guava), and nuts. These are rich in antioxidants, vitamins, and minerals needed to maintain the reproductive system. Foods like sesame seeds and jaggery are also taken as natural fertility enhancers in Indian traditional diets.

Pro Tip: Eat seasonal food in your everyday diet to boost your reproductive health and keep your hormones in check.

4. Less Stress and Improved Sleep
Winter’s longer nights tend to promote improved sleep, which is necessary for the balancing of hormones. Better quality of sleep would enhance the conditions for ovulation and sperm production, whereas decreased stress improves overall fertility.

Pro Tip: Establish a bedtime routine, enjoy warm beverages like herbal tea, and keep your bedroom cozy to maximize the benefits of winter’s restful nights.

5. Chances of Seasonal Diseases and Weight gain
On the other hand, cold weather may have the impact of increasing the vulnerability of acquiring colds and flu, and might thus weaken the body for some time, along with infertility. Also, minimal movement, calorie-rich foods are the factors that lead to gaining weight, which impacts hormone levels.

Pro Tip: Light exercises like yoga or walking, maintain healthy weight, and keep in your diet immunity-boosting foods like turmeric milk and ginger tea.

Final Thoughts for Couples Trying to Conceive
Winter is indeed the perfect time to focus on one’s reproductive health. But the right approach—healthy eating, stress management, and leveraging nature’s hormonal benefits—can definitely make the most of it. Stay warm, stay hopeful, and remember that this is a journey unique to each couple.

Dr. Sandhya Rani, Sr. Consultant – Obstetrics & Gynaecology, Aster Women & Children Hospital, Bengaluru

Increased reports of period pain have been noticed in recent times. As a young woman, it’s essential to take care of one’s reproductive health. Many complications during this age can affect your entire well-being, from irregular periods to hormonal imbalances and risks of sexually transmitted infections (STIs). Keeping up with common reproductive health problems and learning how to tackle them is imperative for a healthy future.

So, here is what every young woman should know about reproductive health, especially navigating common health concerns.

1.  Irregular Periods – Irregular cycles may be a sign of hormonal imbalances or conditions like PCOS. Track your periods and consult a gynaecologist if they are consistently irregular, heavy or painful. Early intervention can help regulate your cycle.
2.  Severe Pain – Severe period pain is not normal. It may be a sign of endometriosis or fibroids. If severe pain interferes with your daily life, consult a doctor for proper diagnosis and treatment. Complications can be avoided and one’s daily life can be improved simply by recognising and treating these signs early.
3.  Infections and STIs – Most infections and sexually transmitted infections (STIs) can be prevented. Hence practice safe intercourse, take regular screening tests and maintain good hygiene to protect your health. Pelvic inflammatory disease is one of the most common consequences of untreated infections leading to severe issues.
4.  Fertility Awareness – PCOS or pelvic infections can cause fertility issues. Consult a doctor if you have any concerns or are planning for the future. Regular check-ups can result in early identification of any issues and help doctors to provide specific solutions.
5.  Hormonal Imbalances – Mood swings, acne or changes in a person’s body could be symptoms of hormonal issues. Consult a gynaecologist about persistent symptoms to prevent long-term effects. A well-balanced lifestyle often helps to manage these imbalances.
6.  Contraception Options – Understand and select the appropriate contraceptive that suits your needs. Discussion with your gynaecologist will help you choose the right contraception based on your health and lifestyle. Proper education and information on the different contraceptive options reduce risk and promote safer choices.

Reproductive health isn’t only about disease management, it’s about taking control of one’s health, which involves preventing potential problems and seeking appropriate timely treatment when needed. Staying aware of conditions like irregular periods, hormonal imbalances and sexually transmitted infections can improve your overall health. Maintaining proper reproductive health along with early diagnosis and treatment can prevent bigger problems while contributing to a satisfied life without complications.

New Delhi, February 10, 2025 – The Lodhi, New Delhi, a distinguished member of The Leading Hotels of the World, has added another feather to its cap by unveiling its brand new Pickleball Courts as part of its world class recreational offerings. This exciting new addition complements the already impressive amenities within The Lodhi’s state-of-the-art lifestyle club, elevating the property’s commitment to luxury, wellness, and active living.

 On February 3, 2025 The Lodhi hosted a glamorous launch event for its three newly introduced Pickleball courts, welcoming an elite gathering of sports enthusiasts, luxury lifestyle connoisseurs, and guests eager to experience one of the world’s fastest-growing sports in a premium setting. The event, held from 4:30 PM to 6:30 PM at The Lodhi’s state-of-the-art courts, was a thrilling celebration of athleticism and camaraderie. The Lodhi has introduced 3 Pickleball courts, providing ample space for players to engage in fast-paced matches. Attendees were treated to an engaging showcase of Pickleball, with live matches featuring sports enthusiasts demonstrating the strategic gameplay.

 The Lodhi’s lifestyle club features an impressive range of facilities, including 8000 Sq. ft. of a fully equipped gymnasium, Pilates and spin studios, squash courts, table tennis, lawn tennis courts, and a 50-meter lap pool. The addition of Pickleball courts further enhances these offerings, ensuring that residents and guests can engage in both traditional and contemporary sports in an elegant environment.

 To ensure an exceptional playing experience, The Lodhi partnered with Elephant Racquet Club, which supplied high-quality racquets and balls designed for superior performance. This collaboration underscored the hotel’s commitment to providing the best equipment for both seasoned players and newcomers eager to learn the sport. Meanwhile, XTCY Drinks kept the energy levels high with a curated selection of refreshing and revitalizing beverages, ensuring that players and guests remained hydrated and invigorated throughout the evening.

 The event also featured a gourmet spread of light bites and refreshments crafted by The Lodhi’s renowned culinary team. Guests indulged in an assortment of healthy yet delectable treats designed to complement the active nature of the evening. The lively ambiance was further enhanced by curated music, adding a dynamic touch to the celebratory occasion.

 Commenting on the successful launch, Abhimanyu Lodha, General Manager of The Lodhi, New Delhi, said: “We are thrilled to introduce Pickleball to our distinguished guests and patrons. The Lodhi has always been at the forefront of blending luxury with wellness, and these new courts further our commitment to providing world-class recreational facilities. We look forward to fostering a vibrant sporting community and offering unique experiences for all our guests.”

 With the successful launch of its Pickleball courts, The Lodhi reinforces its reputation as a leader in luxury hospitality, blending wellness, recreation, and sophistication. These new courts are set to become a premier sporting destination in the capital, offering guests and members an unparalleled experience in a world-class setting.

 As Pickleball continues to gain global recognition, with premium facilities, expert coaching, and an unmatched luxury experience, The Lodhi remains at the forefront of redefining elite leisure and wellness in New Delhi.

Gurugram, 10th February 2025: In an endeavor to create awareness about cancer, Fortis Memorial Research Institute, Gurugram along with (HMCI) Heritage Motoring Club of India today flagged off a vintage car rally from the hospital. The event, flagged off at 9:45 AM by Mr. Yash Rawat, Facility Director, Fortis Gurugram in the presence of Cancer Survivors, Fortis Senior Clinicians, and Fortis Senior Leadership all uniting to highlight the critical themes of early detection, effective treatment options, and the resilience necessary to conquer cancer.

The rally demonstrated a robust turnout with over 400 participants, including 45 vintage cars and vintage motorcycles. Following the flag-off from Fortis Gurugram, the drivers embarked on their journey covering a total distance of 12.7 km from Baktawar Chowk, 32 milestone (sector 29) and back to Fortis Memorial Research Institute, Gurugram. The event brought together esteemed senior oncologists from the Fortis Group, who shared their insights and perspectives on the significance of cancer prevention and care.

Yash Rawat, Facility Director, Fortis Gurugram, said, “It’s truly inspiring to witness the unwavering passion and enthusiasm of the drivers who joined this awareness initiative. Their dedication sends a powerful message about the importance of early detection, effective treatment, and the relentless spirit required to combat cancer. As India faces a challenging fight against this disease in the coming years, Fortis, as a leading healthcare provider, is taking significant steps to enhance treatment and care for cancer patients. Our survivors are a source of inspiration, demonstrating that life after cancer is not just about surviving, it’s about thriving with confidence and dignity. At Fortis Gurugram, we are committed to providing not only world-class medical treatment but also emotional and psychological support to empower every patient on their journey. Today, we celebrate their courage and unwavering spirit.”

Diljeet Titus, General Secretary, Heritage Motoring Club of India said, “The rally aimed to raise awareness about the prevalence of cancer in India while stressing the importance of early detection and regular screening. The rally was designed to inspire and support cancer survivors and patients, highlighting their courage and determination. It also fostered community engagement and support, representing more than just an event-it symbolised a movement towards a cancer-aware society. The rally embodies hope, strength, and collective determination to conquer cancer. Fortis Healthcare’s commitment, combined with the support of the Heritage Motoring Club community, sends a powerful message in the battle against cancer. Together, they drive not only for awareness but for a future where cancer is no longer a feared adversary.”