World Health Day: Experts call for equitable access to healthcare for blood cancer and blood disorder patients

HYDERABAD, 10th April 2024: 25-year-old Puneeth suffered from thalassemia major, which is a genetic blood disorder characterized by abnormal hemoglobin production and low production of red blood cells since he was only nine. Battling with thalassemia as a child came with multifaceted challenges in Puneeth’s day-to-day activities.

Since Puneeth was diagnosed with this disease in 2008, he has undergone blood transfusions at a charitable hospital on a regular basis. A stem cell transplant was the only curative treatment option for Puneeth’s condition. It was only in 2020 when a Hospital in Bangalore conducted a free HLA typing camp in association with DKMS-BMST at their centre, where Puneeth and his elder brother Prajwal gave their cheek swab sample for HLA (Human Leukocyte Antigen) typing. The result showed that Puneet found a perfect match with his brother.

However, owing to financial constraints, his family was hesitant towards the transplantation. This is where the DKMS BMST Patient Funding program stepped in to help Puneeth successfully undergo his transplant in September 2022 and receive a second chance at life. The transplant yielded success, and the family now looks forward to a positive future ahead.

Puneeth was fortunate enough to find a matching donor in his family, whereas over 70% of the patients diagnosed with blood cancer or blood disorder are unable to find a match and urgently need a matching unrelated donor. DKMS-BMST has a mission to give such patients a second chance at life by registering potential stem cell donors from across India.

Dr. Nitin Agarwal, MD Transfusion Medicine, HOD, Donor Request Management, DKMS BMST Foundation India, said, “India sees a high prevalence of blood cancer and blood disorder cases, with a mortality of over 70,000 and an incidence of over 100,000 annually, significantly impacting our healthcare system. Patients often face numerous challenges, including financial constraints and the lack of awareness about available treatment options. Stem cell transplant is a crucial intervention that offers a ray of hope for patients battling these diseases, providing them second chance at life.”

Patrick Paul, CEO of DKMS BMST Foundation India, said, “Aligned with the theme of World Health Day “My Health, My Right,” we believe that everyone, regardless of background or circumstance, deserves access to quality health services, information, and the resources needed to live a healthy life. Through the Patient funding and and Thalassemia programs, DKMS-BMST has been instrumental in democratising access to stem cell transplantations nationwide. To achieve this, we have created an effective and streamlined program structure so we can help as many patients in need as possible. By alleviating financial constraints and fostering collaborations within the healthcare sector, we strive to empower individuals like Puneeth with the opportunity for enhanced quality of life and renewed hope.”

While advancements in medical science have improved outcomes for blood cancer and blood disorder patients, a significant hurdle remains – the availability of Human Leukocyte Antigen (HLA)–matched stem cell donors. An HLA match is crucial for a successful stem cell transplant, and the likelihood of finding a match is highest among individuals of similar ethnicity.

The current pool of potential stem cell donors is insufficient to meet the needs of all blood cancer and blood disorder patients. This disparity disproportionately affects Indian patients, who have a lower chance of finding a match due to limited donor diversity. Unfortunately, only 0.03% of the Indian population have registered as potential donors. This increases the need for more people of Indian ethnicity to register themselves.

To register as a potential stem cell donor, you must be a healthy Indian adult between 18 and 55. When you are ready to register, all you need to do is complete a consent form and swab the inside of your cheeks to collect your tissue cells. Your tissue sample is then sent to the lab to be analyzed for your HLA (Human Leukocyte Antigen) and listed anonymously on the international search platform for matching stem cell donors. If you’re eligible, register as a blood stem cell donor by ordering your home swab kit at www.dkms-bmst.org/register

Enhanced rock weathering results in higher crop yields and improved crop health

Enhanced rock weathering – a nature-based carbon dioxide removal process that accelerates natural weathering – results in significantly higher first-year crop yields, improved soil pH, and higher nutrient uptake, according to a new scientific paper, released in PLOS ONE today.

Enhanced rock weathering (ERW) involves spreading finely crushed silicate rock such as basalt on agricultural land. It is a scalable and permanent climate technology with the potential to sequester gigatonnes of carbon dioxide from the atmosphere. Co-authored by scientists at UNDO, a leading enhanced rock weathering project developer, and Newcastle University, the peer-reviewed publication is the latest enhanced rock weathering (ERW) study assessing the impact on crops in a temperate climate.

Dr XinRan Liu, Head of Science and Research at UNDO and co-author of the paper, commented: “Nutrient limitations in agricultural soils are a major concern for farmers about sustaining and increasing crop yields. This latest study highlights how the spreading of basalt rock on farmland can lead to higher crop yields and can be effective in a temperate climate. This research demonstrates the potential for enhanced rock weathering to contribute to improved farmer livelihoods and food production, whilst also removing CO2 from the atmosphere.”

The results from the ongoing trial’s first year demonstrate that the crop yield was on average 15% higher (9.3% and 20.5% between plowed and direct drill amended plots respectively) across two different cultivation techniques.

The trial results also showed a stabilizing effect on the soil pH, with the soil pH being on average 0.2 and 0.29 pH units higher in the basalt-amended plots, compared to the control plots. This change is a result of alkaline products generated as the rock minerals dissolve. The effect of silicate mineral dissolution on the soil pH could represent an attractive agronomic benefit for farmers as an elevated soil pH allows crops to access more nutrients in the soil.

Basalt rock is rich in minerals that slowly release nutrients during dissolution. These nutrients act as a natural soil amendment and are essential for plant growth. The study found higher nutrient concentrations in the crops grown in the basalt-amended soil, including tissue calcium, grain, and tissue potassium, suggesting that ERW can boost nutrient availability for plants and, as a result, may improve crop yield.

Taking account of the unusually dry growing season conditions in 2022, these findings indicate that basalt amendment could enhance productivity and crop yields, contributing to more sustainable and resilient food production systems in the face of future changes in growing season weather as a result of global warming.

Professor David Manning, Professor of Soil Science, Newcastle University, and co-author of the paper, commented: “The results of this trial give further scientific credibility for enhanced rock weathering and greatly improve its value proposition to farmers. Newcastle University is pleased to partner with UNDO. Our joint research into the co-benefits for farmers of basalt amendment is helping to pave the way for the widespread adoption of enhanced rock weathering in the agricultural community.”

The trial results also show no additional toxic elements taken up by crops in the plots where basalt had been spread. There was no negative impact on the natural environment in this trial, which indicates the food produced from it is safe for consumption. UNDO’s basalt has been approved for use in organic farming systems by respected certification bodies such as the Soil Association.

Yit Arn Teh, Professor of Soil Science, Newcastle University, said: “Independent bodies, such as the IPCC and UK Committee for Climate Change, have repeatedly highlighted the urgent need for climate action in the agriculture and land use sector to counter the effects of dangerous climate change. At the same time, the agricultural sector is under increasing pressure to meet key sustainability and environmental targets, against a backdrop of rising farm operating costs, driven by the cost of living crisis.

“Use of enhanced rock weathering to remove carbon dioxide and naturally enhance soil health represents a potential win-win for farmers and climate as this technology is able to capture carbon dioxide while simultaneously supplying some of the key nutrients that crops require for successful growth. By using locally-sourced rocks, rather than inputs (e.g. fertilizers) obtained from overseas, supply chains are also shortened, further reducing the overall carbon footprint of food production.

“Crucially, enhanced rock weathering is a technology that can be readily adopted by the agricultural sector because it does not require farmers to invest in new equipment, technology or training, but simply utilizes the existing equipment and infrastructure for spreading fertilizer or other soil amendments.”

The authors of the paper hope that the agronomic co-benefits of enhanced rock weathering will further incentivize farmers across the UK and worldwide to take advantage of this nature-based carbon removal solution.

Goji berries and diabetes

When your blood glucose or blood sugar is too high, you might have diabetes. Your body uses glucose as its primary energy source as it can also produce glucose when consumed in daily food. Goji berries are good for treating diabetes, but several individuals are unaware of their benefits or what exactly they are. Goji berries are tiny red fruits that provide extra energy and power because they are rich in beneficial antioxidants. Goji berries have several health advantages as support for immune system function, glycemic management, and anti-aging properties.

Another name for goji berries is Lycium barbarum. The goji berry is indigenous to Asia and has been used as a food supplement for over 2000 years as a medicinal plant. Goji berries may help to regulate blood sugar. Goji berries regulate blood glucose and insulin levels and are associated with higher HDL levels in T2D patients and are also known as “good” cholesterol, HDL.

It is a “superfood” because it has a chemical component called phytochemicals that has polysaccharides, beta-carotene, and zeaxanthin. A study found that the polysaccharides in goji berries enhanced the body’s overall antioxidant activity and bolstered the immune system. Beta-carotene, a compound that gives goji berries their orange-red hue. Zeaxanthin is an essential component that helps to maintain the immune system. Zeaxanthin is thought by several researchers to be able to stop macular degeneration, a progressive visual impairment that develops as the macula, the center portion of the retina, deteriorates.

Goji berries contain dietary fiber that can lower blood sugar levels by delaying the body’s absorption of glucose. It encourages fullness, which can help with weight management and another crucial aspect of managing diabetes. Flavonoids and carotenoids, two types of antioxidants found in these berries, may help lower oxidative stress and inflammation linked to the consequences of diabetes. Goji berries are a healthy addition to a diabetic diet, but moderation is key when consuming them. They are high in calories, just like any other dried fruit, and consuming a lot of them might raise blood sugar levels.

Goji berries should only be added to a diet with caution if you use medication to control diabetes. Blood thinners and medications that lower blood sugar levels may interact with them. Before making any major dietary changes, speak with your healthcare physician. Keep in mind that controlling diabetes entails more than merely consuming or avoiding particular meals. It’s critical to concentrate on eating a well-balanced diet full of entire foods, such as fruits, vegetables, lean meats, and healthy fats. Other crucial aspects of managing diabetes are stress reduction, proper hydration, and regular physical activity.

Goji berries can be incorporated into a diabetic’s diet. Individual needs and preferences do, however, differ, so it’s crucial to speak with a medical professional or certified dietitian for tailored nutritional advice based on your objectives and unique health situation.

Preeti Nagar

According to Preeti Nagar, Dietician at NIIMS College and Hospital, NIU- Goji berries cause blood sugar levels to rise more slowly because of their comparatively low GI. Those who have diabetes may benefit from this, as it helps avoid sharp rises in blood sugar. Iron, zinc, selenium, vitamin C, and other antioxidants are among the many vitamins, minerals, and nutrients that they are high in. These nutrients have the potential to improve general health and may be especially helpful for those who have diabetes, as they may require more nutrients. Goji berries should only be added to your diet with caution if you use medication to control diabetes. Particularly, blood thinners and medications that lower blood sugar levels may interact with them. Before making any major dietary changes, speak with your healthcare physician. It’s critical to concentrate on eating a well-balanced diet full of entire foods, such as fruits, vegetables, lean meats, and healthy fats.

Hyderabad Based Moderate launches Let’s keep it Moderate Campaign, Introducing Themed days for Health & Wellness Engagement

Hyderabad, 9th April 2024: Moderate, a leading advocate for holistic well-being, introduces its latest initiative, “Let’s keep it Moderate,” aimed to empower individuals with valuable insights and practical tips for maintaining a healthy lifestyle. This initiative serves as a valuable resource for people to understand the right choices regarding their dietary habits and provides solutions for addressing the rising sugar & weight epidemic. Driven by the company’s commitment to promoting overall health, this social media campaign introduces Themed Days to promote Health & Wellness engagement. Spearheaded by founder Dr. Lalitha Palle, the campaign delivers expert guidance through engaging weekly blog series, enriching the community with actionable advice and inspiration.

This campaign will commence with its first themed day, Low-Carb Mondays, which will focus on low-carbohydrate meal ideas, recipes, and tips for reducing carb intake. Users will have the opportunity to participate by sharing their favorite low-carb dishes, strategies for meal planning, or success stories related to carb-conscious eating. Following Low-Carb Mondays will be Workout Wednesdays, prioritizing encouraging users to share their workout routines and exercise challenges. Subsequently, Healthy Snack Fridays will highlight healthy snack options, quick recipes, and creative snack ideas that promote nutritious eating habits as the weekend approaches. Lastly, to conclude the week, Self-Care Sundays will emphasize self-care practices, mental health tips, relaxation techniques, and mindfulness exercises.

Speaking on this initiative, Dr. Lalitha Palle, Founder of Moderate said, “We are excited to unveil this innovative and engaging health campaign, leveraging the power of social media to revolutionize wellness. With this initiative, we aim to amplify awareness about sustainable healthy lifestyle choices, the vital pillars of health, fitness, nutrition and inspiring a larger community to embrace and champion healthy living.”

Participating in such themed days will enable every individual to engage with the Moderate community, discover new resources, and glean insights from each other’s journeys towards healthy living and life balance. Moderate has been providing a sustainable way to help achieve a consistent low-carb diet and maintain a healthy life balance, so stay tuned for further updates and captivating methods to engage in this innovative and health-conscious social media campaign, to learn more from the experts, and discover captivating methods to engage in this innovative health-conscious social media campaign. This initiative will not only encourage users to prioritize self-care and share their favorite self-care rituals and mindfulness activities but also prompt reflection on personal growth and well-being.

Moderate Launches ‘Let’s Keep it Moderate’ Campaign, Introducing Themed Days for Health & Wellness Engagement

9th April 2024: Moderate, a leading advocate for holistic well-being, introduces its latest initiative, “Let’s keep it Moderate,” aimed to empower individuals with valuable insights and practical tips for maintaining a healthy lifestyle. This initiative serves as a valuable resource for people to understand the right choices regarding their dietary habits and provides solutions for addressing the rising sugar & weight epidemic. Driven by the company’s commitment to promoting overall health, this social media campaign introduces Themed Days to promote Health & Wellness engagement. Spearheaded by founder Dr. Lalitha Palle, the campaign delivers expert guidance through engaging weekly blog series, enriching the community with actionable advice and inspiration.

This campaign will commence with its first themed day, Low-Carb Mondays, which will focus on low-carbohydrate meal ideas, recipes, and tips for reducing carb intake. Users will have the opportunity to participate by sharing their favorite low-carb dishes, strategies for meal planning, or success stories related to carb-conscious eating. Following Low-Carb Mondays will be Workout Wednesdays, prioritizing encouraging users to share their workout routines and exercise challenges. Subsequently, Healthy Snack Fridays will highlight healthy snack options, quick recipes, and creative snack ideas that promote nutritious eating habits as the weekend approaches. Lastly, to conclude the week, Self-Care Sundays will emphasize self-care practices, mental health tips, relaxation techniques, and mindfulness exercises.

Speaking on this initiative, Dr. Lalitha Palle, Founder of Moderate said, “We are excited to unveil this innovative and engaging health campaign, leveraging the power of social media to revolutionize wellness. With this initiative, we aim to amplify awareness about sustainable healthy lifestyle choices, the vital pillars of health, fitness, and nutrition, and inspiring a larger community to embrace and champion healthy living.”

Participating in such themed days will enable every individual to engage with the Moderate community, discover new resources, and glean insights from each other’s journeys towards healthy living and life balance. Moderate has been providing a sustainable way to help achieve a consistent low-carb diet and maintain a healthy life balance, so stay tuned for further updates and captivating methods to engage in this innovative and health-conscious social media campaign, to learn more from the experts, and discover captivating methods to engage in this innovative health-conscious social media campaign. This initiative will not only encourage users to prioritize self-care and share their favorite self-care rituals and mindfulness activities but also prompt reflection on personal growth and well-being.

Sakra World Hospital Successfully Performs 100 Robotic GI Surgeries, Enhances Patient Outcomes

Bengaluru 9th April 2024: Sakra World Hospital, a pioneering healthcare facility in India funded entirely by foreign direct investment (FDI), has completed 100 robotic gastrointestinal (GI) surgeries. In the medical field, robotic-assisted surgical procedures are steadily on the rise. The increasing acceptance of robotic surgeries can be attributed to their accuracy, minimally invasive techniques, and capacity to improve surgical outcomes. With a group of skilled surgeons and cutting-edge facilities, Sakra World Hospital has become a pioneer in leveraging this technology to help patients suffering from gastrointestinal surgical issues.

Robotic-assisted surgery enables the performance of intricate procedures across a wide spectrum, including colorectal cancers, and benign and malignant conditions of the liver, biliary system, and pancreas, apart from complex hernia repairs, gallbladder removals, and abdominal wall reconstruction. With a focus on less trauma and greater precision in these surgical interventions, Sakra tremendously benefits patients specializing in upper gastrointestinal surgeries, such as giant hiatal hernias, gastroesophageal reflux disease (GERD), Heller’s myotomy, and even uncommon conditions like median arcuate ligament syndrome.

“We take immense pride in reaching a significant milestone in robotic GI surgeries, underscoring the skill and commitment of our proficient surgical team,” lauded Lovekesh Phasu, Chief Operating Officer, Sakra World Hospital, Bengaluru, adding, “At Sakra, we’re committed to setting high standards and achieving them, to benefit our patients and provide quality healthcare for all.”

The application of robot-assisted technologies has greatly improved surgical capabilities in GI surgeries. These systems are operated directly by surgeons, in contrast to autonomous systems, which enable careful dissection around target organs. Although laparoscopic surgery provides benefits such as accurate dissection under high-resolution imaging and minimally invasive procedures, it has limitations due to the limited dexterity of the instruments. These limitations are overcome by the existing robotic system’s articulated instruments, vibration filtering, and motion scaling functions. These capabilities allow surgeons to perform more versatile surgeries than they could with standard laparoscopic equipment.

Moreover, the robotic system’s instruments with wrist-like movements and dexterity assures delicate tissue handling and precision surgery with minimal bleeding. This capability, coupled with three-dimensional magnified, enhanced imaging, provides a platform wherein complex procedures in critical places and organs can be safely performed. Through these innovations, robotics surgery in the gastrointestinal realm continues to push boundaries, enhancing surgical precision and expanding treatment options for patients.

Robotic GI surgery has emerged as a reassuring alternative to traditional methods, dispelling common fears. The robotic system not only provides surgeons with better visualization and precision, but the patient also benefits from smaller incisions, less blood loss, quicker recovery, and reduced post-operative pain.

“The completion of 100 robotic GI surgeries at Sakra World Hospital not only marks a numerical achievement but also serves as evidence of the hospital’s steadfast dedication to delivering top-notch care to its patients,” remarked Dr Sadiq Saleem Sikora, Director of Gastrointestinal Surgery and Liver Transplantation at Sakra World Hospital, Bengaluru.

Dr D. Nageshwar Reddy inaugurates the Gastroenterology Department and Deluxe Rooms at Mahavir Hospitals

Dr D. Nageshwar Reddy inaugurates

Hyderabad,8th April 2024 …. The Gastroenterology Department and Deluxe Rooms opened at Mahavir Hospital & Research Center at Mahavir Hospital at Masabtank, Hyderabad

Dr. D. Nageshwar Reddy, Chairman & Founder, Asian Institute of Gastroenterology inaugurated the same.

Speaking on the occasion, Dr D. Nageshwar Reddy, a well-known doctor in Gastroenterology across India said Mahavir Hospital has been doing a lot of yeoman service for many years

The gastroenterologist specialization looks at disorders and diseases that affect the digestive system — including the gastrointestinal tract (esophagus, stomach, small intestine, large intestine, rectum and anus), as well as the pancreas, liver, bile ducts and gallbladder etc, is most important. The diseases related to this are on the rise and facilities like this are most welcome, Dr D. Nageshwar Reddy said.

Mahavir Hospital with a reputation of over four decades of serving the poor and needy regardless of religion, caste & creed, is now committed to upgrading all departments with the latest equipment for better health care of the patients, the hospital release said.

The Gastroenterology wing was donated by Smt Chandrakaladevi Kantilal Nahar and his Family. Gastroenterology Department Equipment was supported by hubergroup.

The deluxe ward donors are Sri Hanumanmal Suman Nakhat & Family; Sri Prakash Kamdar & Family, Shri Satish Dr. Asha Khivasara & Family; Sri Mahadeerachand Vijayalaxmi Chopra & Family; Sri Ghewarchand Vinayakiya & Family, Sri Lalith Bhansali & Family, Sri Rupender Sunil Anvil Vishal Ostwal & Family; JITO Ladies Wing; Sri Anil Saraswati Devi Bhojani & Family; Sri Gauthamchand Kamladevi Gugalia & Family and Sri Sthankwasi Chandanbala Mahila Mandal.

Dr. Rupendra Prasad, MD, Gastroenterology Department Head, Mahendra Ranka, Chairman; Sushil Kapadia, Vice Chairman, Sushil Sancheti Trustee Treasurer, Sushil Pahade, Managing Trustee; standing committee members Dr Asha Khivsara, Dr, Ghisulal Jain, Nitin K Shah, Paresh Shah, Rajesh Parak, Rajesh Pokerna, Ramesh Kundalia, Sheel Kumar Jain, Vijay Surana, Vimal Ranka, Yogesh Jain and all trustees participated in the inaugural function.

A Vision of Hope: Nand Ghar’s Healthcare Interventions Transforming lives in Jharkhand

A Vision of Hope

Ranchi, 8th April 2024: On this World Health Day, amidst global reflections on healthcare access and empowerment, Nand Ghar emerges as a shining example of transformative change. Nand Ghar, a flagship women and child welfare project under the Anil Agarwal Foundation, the social impact arm of Vedanta, is weaving a brighter future for countless citizens across India. This project consists of a network of modern Anganwadis that goes beyond traditional childcare, offering a comprehensive approach to well-being. By addressing early childhood education, nutrition, and health needs alongside skill development and economic empowerment of women, Project Nand Ghar empowers communities and fosters a healthier tomorrow.

At the heart of Nand Ghar’s mission lies a steadfast commitment to improve healthcare outcomes and increase its access for local communities across India through various interventions. One such instance of the project’s impactful healthcare interventions comes from Jharkhand, where Musri Devi, a senior citizen living inMadhunia village in Chas Panchayat, Bokarowas helped by Nand Ghar to overcome her health struggles. Musri Devi was leading a tough life with no support from her two married sons or the village community. She lived alone with her husband and depended on his irregular income as a daily wage laborer. Suffering from a blurry vision, she was struggling to carry out her daily chores as well.

She ignored the problem for the longest time since she assumed it to be a result of her old age. However, at a free eye check-up camp organized by the Nand Ghar in her village, Musri Devi received the attention she needed. She was diagnosed with cataracts and was offered the right guidance from a set of dedicated healthcare professionals associated with Nand Ghar. Musri Devi underwent a successful surgery, restoring her eyesight and rejuvenating her outlook on life.

The impact of Nand Ghar extends far beyond such individual success stories. Through the Project, AAF has positively impacted more than 2,20,000 children aged 0-6 years, in addition to 1,00,000pregnant and lactating women, a reach of around 58,00,000 community health program beneficiaries, and more than 1,70,000 women through its skilling program. The integrated healthcare model of Nand Ghar has resulted in building healthier communities. Each cluster of 25-30 Nand Ghars is equipped with Mobile Medical Units (MMUs) or a telemedicine kit or conducting regular health camps, staffed with doctors and paramedics, to provide essential primary healthcare services. These services not only offer immediate medical aid but also facilitate referrals for emergency or critical cases to the nearest Community Health Centre.

As AAF continues its journey towards empowering communities, transforming lives, and facilitating sustainable growth, Nand Ghar remains at the forefront, championing the cause of healthcare access among communities.

Marengo Asia Hospitals Gurugram launched the Bone Marrow Transplant department

Marengo Asia Hospitals

Marengo Asia Hospitals Gurugram launched the Bone Marrow Transplant unit today to provide exceptional clinical excellence for patients in Gurugram and surrounding areas for bone-related diseases that have few options other than treatment with a bone marrow transplant. The team at the hospital leading the department is headed by Dr Meet Kumar, Clinical Director, Haematology & Bone Marrow Transplant, Marengo Asia Hospitals. He is supported by Dr Neeraj Teotia, Consultant- Pediatric Hemato-Oncology & Bone Marrow Transplant.

Marengo Asia Hospitals Gurugram has been consistently raising increased awareness and busting a few myths about blood-related disorders and the recent advancements made in the treatment of ailments. Highlighting the fact that hardly 10% of the population is aware of the symptoms and treatment modalities for blood-related ailments, the hospital has hosted several events to amplify the rising number of cases of blood-related diseases.

Dr Meet Kumar, Clinical Director, Haematology & Bone Marrow Transplant, Marengo Asia Hospitals Gurugram said “Blood disorders are one of the most fatal forms of cancer that severely impacts the quality of life. Raising awareness that these diseases can be permanently cured through Bone Marrow Transplant is crucial. With recent technological advancements, previously considered deadly blood disorders such as Acute Leukaemia, Multiple Myeloma, Aplastic Anaemia, Thalassemia Major, sickle cell disease, and various other cancers can now be successfully treated with Bone Marrow Transplant (BMT) when conventional therapies like chemotherapy and radiotherapy fail.”

BMT is indicated for various conditions, including blood cancers, thalassemia, sickle cell anemia, immune deficiencies, aplastic anemia, certain autoimmune disorders, and, more recently, some solid Tumors such as brain tumors, neuroblastoma, and sarcomas. Common symptoms of blood disorders that require BMT include thalassaemic patients requiring monthly blood transfusions from the age of six months, aplastic anemia patients presenting with weakness, tiredness, persistent fever, or bleeding spots on the body, and blood cancer patients experiencing weakness, tiredness, increased infection risk, and bleeding.

With the progress in hematology and stem cell transplantation, Bone Marrow Transplants (BMT) have emerged as the ultimate life-saving remedy for even previously untreatable and potentially deadly conditions. The bone marrow plays a crucial role in blood cell production, and BMT involves the replacement of damaged or dysfunctional bone marrow with healthy cells. This procedure is broadly classified into two types: Allogenic, which utilizes a donor with compatible tissue, and Autologous, wherein the patient’s stem cells are used. Recent advancements have enabled the viability of haploidentical transplants, where successful transplantation is achievable even with a donor tissue match of just 50% or partial identity. Such innovations have significantly reduced the waiting time for many patients urgently requiring a BMT.

Dr. Raajiv Singhal, Managing Director & Group CEO, of Marengo Asia Hospitals said “As we inaugurate our Bone Marrow Transplant unit today, we embark on a journey of amplifying awareness regarding blood-related disorders and the advanced treatment modalities; a journey of hope, healing, and pioneering medical care; and to aid the common public with the right information and awareness. We reinforce our commitment to providing comprehensive healthcare solutions, pushing the boundaries to offer renewed hope to families battling bone marrow disorders. Through the advocacy of preventive measures/recognizing early symptoms and the dissemination of insights into modern and advanced treatment modalities, armed with super-specialized clinical excellence and skilled professionals, our mission encompasses mitigating the prevalence of this ailment.”

Neeta Rajwar, Facility Director, Marengo Asia Hospitals Gurugram said, “Marengo Asia Hospital remains resolutely committed to steering public health discourse through initiatives akin to this awareness assembly. By fortifying understanding and response to advanced treatment modalities to cure blood disorders, the hospital actively contributes to a more robust, enlightened, and resilient community, better equipped to counter the adversity of such deadly ailments.”

In India, approximately 2,500 to 3,000 Bone Marrow Transplants (BMT) are performed each year now in contrast to only 500, 3 years ago. However, the demand for BMT far exceeds the number of transplants being conducted. The scarcity is primarily due to a lack of awareness, inadequate infrastructure, and a shortage of skilled physicians. Bone Marrow Transplants (BMTs) are on a steady rise in India, with about 2,500 transplants being performed yearly unlike five years ago when it was less than 500. The number of BMT centers is increasing, and the rapid expansion of bone marrow transplant centers with enhanced infrastructure has been significant. This development has increased the accessibility of super-specialized clinical excellence and improved the efficiency of procedures with advanced techniques and technology.

Aurigene Pharmaceutical Services Ltd. introduces Aurigene.AI™ an artificial intelligence (AI) and machine learning (ML) assisted drug discovery platform

Aurigene Pharmaceutical

Hyderabad, India. 4th April 2024:Aurigene Pharmaceutical Services Limited (Aurigene), a contract research, development, and manufacturing services organization, and Dr. Reddy’s Laboratoriescompany introduces Aurigene.AI, an AI and ML-assisted platform for accelerating drug discovery projects from hit identification to candidate nomination.

Aurigene.AI combines advanced physics-based simulation, generative and predictive AI models, and CADD (Computer-AidedDrug Design)in one platform, allowing users to pick the appropriate algorithms for a given application. The modular platform also consists of a meticulously curated database of 180 million compounds and 1.6 million validated bioassay data points. This database is ever-expanding and serves as training data for the platform.

Aurigene.AI is hosted on Google Cloud, which offers a scalable infrastructure for handling large datasets and efficient computation while safeguarding client data confidentiality.

Integrating AI and ML-based solutions with Aurigene’s core capabilities in chemical design, synthesis, and assessment in bioassays will facilitate faster development of novel therapeutics. Discovery scientists at Aurigene have validated the platform using a case study and demonstrated that the application of Aurigene.AI reduced the cycle time from chemical design to synthesis and testing by 35%.

Akhil Ravi, CEO, Aurigene Pharmaceutical Services Ltd., said,”We are committed to continually advancing our service experience and providing innovative end-to-end solutions to our global partners. Aurigene.AI is an important addition to our small molecule discovery offering and represents a data-driven approach to novel therapeutic development.”

Dr. Gayathri Ramaswamy, Global Head of Discovery Services, Aurigene Pharmaceutical Services Ltd.,said, “The addition of AI and iterative machine learning capabilities to our core expertise in synthesizing and testing molecules will significantly reduce the DMTA cycle time in the discovery process. Aurigene.AIaugments our core scientific capabilities in the small molecule discovery space and will serve as an efficient engine towards identifying a drug candidate.”